Slideshow Image 1
Slideshow Image 1
Slideshow Image 2
Slideshow Image 2

COLLECTIONS

Shop collections featuring our clinically proven products

Shop Now

Free Shipping

On all orders over £100 to the UK & N. Ire

Shop Now

LIMITED-EDITION COLLECTION

Youth Radiance Collection

The iS Clinical Youth Radiance Collection delivers a complete anti-ageing experience, deeply hydrating and revitalising tired skin. This advanced collection targets fine lines, wrinkles, and dryness, featuring the cult-favourite Youth Intensive Crème and Youth Eye Complex—clinically formulated for smoother, radiant, and youthful-looking skin.

SHOP NOW
Banner Image
Banner Image

iS Clinical Skin Quiz

Stop Guessing Start Glowing

Your skin is unique and your skincare should be too. Introducing the iS Clinical Skin Quiz: a clinically developed tool designed by skincare experts to assess your skin type, identify key concerns, and recommend a targeted regimen from our award-winning range.

UNLOCK YOUR BEST SKIN EVER
Take the IS CLINICAL Skin Quiz

Shop By Skin Concern

RENEW | DEFEND | HYDRATE

NEW Daily Dynamic Hydrator

This high performing 3-in-1 formula helps to treat visible signs of aging, defends against daily environmental stressors, and delivers deep, lasting hydration that renews the skin. Powered by GeneXC® Technology, this advanced formulation combines an exclusive potent blend of Vitamin C and Extremozymes® to visibly brighten and protect the skin. Exosomes and a powerful peptide aid in visibly improving firmness, elasticity and smoothing fine lines while proactively defending from further signs of aging.

VIEW

Experience an iS Clinical Treatment

Find one of our approved practitioners in your area

Fire and Ice Treatment

From the Blog

Paris Fashion Week: Backstage Skin Protocol for Glowing Skin

Paris Fashion Week: Backstage Skin Protocol for Glowing Skin

At Paris Fashion Week, flawless skin is just as important as the fashion itself. Behind the scenes at the Isabel Marant Ready-to-Wear show, our iS...

Read more
Mother’s Day Gift Guide 2026: Pamper Mum with Radiance

Mother’s Day Gift Guide 2026: Pamper Mum with Radiance

This Mother’s Day, celebrate the incredible women in your life by giving the gift of radiant, youthful skin. iS Clinical offers clinically-proven, high-performance skincare that...

Read more
Discover the Power of Advanced Hydration

Discover the Power of Advanced Hydration

iS Clinical’s Hydration range is expertly formulated to prep and protect skin from dryness and dehydration while reinforcing the skin barrier. Powered by clinically proven...

Read more
Expert Care for Mature Skin: Dermatology-Led Care

Expert Care for Mature Skin: Dermatology-Led Care

With mature skin, hydration can be more complex and many serums simply don’t deliver enough. Dr Anjali Mahto, founder of Self London and author of The Skincare Bible,...

Read more
Key Skincare Ingredient: Acacia Oil

Key Skincare Ingredient: Acacia Oil

Acacia Oil is a nourishing botanical oil prized for its ability to hydrate, calm, and protect the skin. 

Read more
The iS Clinical Fire & Ice Facial: Your Path to Radiant Skin

The iS Clinical Fire & Ice Facial: Your Path to Radiant Skin

Experience the iS Clinical Fire & Ice Facial, a quick, effective treatment that resurfaces skin for a smooth, glowing complexion—no downtime required. Looking for a...

Read more

Follow us @isclinical_uk

Subscribe to our newsletter

Sign up to our newsletter to receive expert skincare advice, product news and 10% off your first iS Clinical order.

Join to get special offers, free giveaways, and once-in-a-lifetime deals.

Botanical

Medical Grade Skincare

Results Driven

Clinically Proven